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half the sample pool was treated with dapoxetine 60 mg + tadalafil 20 mg; the opposite half were treated with dapoxetine 60 mg + sildenafil 100 mg. These plasma samples were then analyzed using fluid chromatography-tandem mass spectrometry. The results showed that dapoxetine didn't alter the pharmacokinetics of tadalafil or sildenafil.
